Tuesday, December 25, 2012

IV PPI in PEPTIC ULCER +/- Bleeding

Peptic ulcer bleeding:             Inj. Omeprazole

40mg  i.v.bolus then
6.7mg/h continuousinfusionx72h(160mg/d  after bolus) OR

80mg i.v. bolus  then  8mg/h  continuous  infusionx72h (192mg/dafterbolus)

Bleeding or severeerosive esophagitis: 40mgi.v.oncedailyfor7to10days

Pathologic hypersecretion/ZollingerEllisonsyndrome Stressulcerprophylaxis :

80mgi.v.every12hours;mayincreaseto80mgevery8hoursifneeded;may titratetohigherdosesdependingonacidoutput 80mgi.v.every12hfor24hfollowedby40

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